Technical success of endoscopic stenting for malignant gastric outlet obstruction

Keywords: malignant gastric outlet obstruction, self-expanding metal stents, endoscopic stenting, duodenal stent, gastric stent

Abstract

Background: Palliation of irresectable malignant gastric outlet obstruction (GOO) using self-expanding metal stents (SEMS) is gaining popularity with high technical success rates. The aim of this study was to review and compare GOO stenting for malignancy with other series.

Methods: A retrospective review of all patients undergoing pyloroduodenal stenting for malignant GOO at Groote Schuur Hospital, 1 March 2018–31 August 2021, evaluating demographics, technical success, pathology, and stent-related complications was done.

Results: One hundred and fourteen patients, of which 38.6% were female, were included, with gastric malignancies (74.6%) being the most frequent underlying pathology. Median age was 64 years (IQR 53–70 years), with 48.2% having at least one comorbidity. The majority (96 patients; 85.7%) required only one stent. In total, 132 stent insertion attempts were undertaken. Three technical failures were experienced (one incorrect stent placement and two failed insertions), equating to a 97.4% technical success rate. Four immediate complications occurred (3.1%): two related to sedation, one incorrect stent placement and an oesophagogastric junction perforation with procedural death. Fifteen delayed complications occurred: 13 tumour in-growth blockages, one stent fracture and one case of poor radial stent expansion. Stent blockages occurred at a median of 107 days (IQR 80–275 days). Salvage stenting was 100% successful in 14 cases requiring re-stenting.

Conclusion: Technical insertion success rates of primary and salvage duodenal stenting for malignant GOO are on par with international high-volume units. The leading pathology locally is gastric adenocarcinoma, with palliative stenting remaining a feasible and accessible option.

Author Biographies

D Tait, University of Cape Town

Department of Surgery, Groote Schuur Hospital, University of Cape Town, South Africa

M F Scriba, University of Cape Town

Upper Gastrointestinal Surgery Unit, Department of Surgery, Groote Schuur Hospital, University of Cape Town, South Africa

C Robinson, University of Cape Town

Department of Surgery, Groote Schuur Hospital, University of Cape Town, South Africa

E G Jonas, University of Cape Town

Surgical Gastroenterology, Department of Surgery, Groote Schuur Hospital, University of Cape Town, South Africa

G E Chinnery, University of Cape Town

Upper Gastrointestinal Surgery Unit, Department of Surgery, Groote Schuur Hospital, University of Cape Town, South Africa

Published
2023-07-31
How to Cite
Tait, D., Scriba, M., Robinson, C., Jonas, E., & Chinnery, G. (2023). Technical success of endoscopic stenting for malignant gastric outlet obstruction. South African Journal of Surgery, 61(4), 33-39. Retrieved from http://sajs.redbricklibrary.co.za/index.php/sajs/article/view/3985
Section
Surgical Oncology